New copper binding components of blood plasma (992.1)

Determination of Copper Content of Human Blood Plasma by an Ion Selective Electrode based on a New Copper-Selectophore

A new selectophore was introduced for Cu2+ ions. Spectroscopic studies showed a selectivity of a new organic compound (L) toward copper ions and several transitional metal ions. Hence, L was utilized in designing several ion selective electrodes for these cations. In practice, Cu2+ ion selective electrode behaved Nernstian (slope of 27.95±0.3 mV decade-1) over a...

On the Form of Copper in Blood Plasma*

Although copper has been the subject of numerous researches which have demonstrated that it is essential for normal hemoglobin formation, there have been very few attempts to discover the type of compound in which the element occurs in the case of red blooded animals. Warburg and Krebs (1) approached the problem in experiments on what was referred to as loosely bound copper in blood serum. Usin...

On the Form of Copper in Blood Plasma*

Although copper has been the subject of numerous researches which have demonstrated that it is essential for normal hemoglobin formation, there have been very few attempts to discover the type of compound in which the element occurs in the case of red blooded animals. Warburg and Krebs (1) approached the problem in experiments on what was referred to as loosely bound copper in blood serum. Usin...

Pathogen reduction of blood components and plasma derivatives

The pathogen safety of plasma derivative and labile blood components has been dramatically enhanced over the last 25 years through the implementation of nucleic acid testing (NAT) technologies that effectively screen out units with high virus titers. Additionally, the incorporation of pathogen inactivation (PI) and removal steps into the manufacturing processes of plasma-derived medicinal produ...

Blood plasma proteins and cellular components as modulators of fibrinolysis